Roger Marthan Selected Research

Gallopamil (D600)

4/2015	Calcium channel blocker reduces airway remodeling in severe asthma. A proof-of-concept study.
6/2011	Airway remodeling in asthma: new mechanisms and potential for pharmacological intervention.

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Roger Marthan Research Topics

Disease

19	Pulmonary Hypertension 12/2021 - 08/2003
18	Hypoxia (Hypoxemia) 12/2021 - 09/2002
17	Asthma (Bronchial Asthma) 01/2022 - 07/2003
10	Inflammation (Inflammations) 01/2022 - 01/2006
6	Airway Remodeling 01/2018 - 12/2007
5	Pulmonary Arterial Hypertension 01/2017 - 06/2004
3	Lung Diseases (Lung Disease) 01/2020 - 06/2002
3	Neoplasms (Cancer) 01/2020 - 01/2017
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2019 - 11/2014
3	Hyperoxia 01/2017 - 02/2002
3	Chronic Obstructive Pulmonary Disease (COPD) 04/2016 - 02/2012
3	Hypertension (High Blood Pressure) 03/2013 - 08/2003
2	Cardiomegaly (Heart Hypertrophy) 01/2020 - 09/2014
2	Lymphoma (Lymphomas) 01/2017 - 04/2015
2	Atherosclerosis 01/2017 - 03/2013
2	Vascular Diseases (Vascular Disease) 01/2017 - 04/2008
2	Fibrosis (Cirrhosis) 01/2016 - 02/2013
2	Right Ventricular Hypertrophy 08/2013 - 01/2013
2	Hypersensitivity (Allergy) 03/2011 - 03/2002
2	Bronchial Spasm 04/2005 - 04/2003
1	Vasculitis (Vasculitides) 02/2022
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2022
1	Infections 01/2022
1	Neuroblastoma 08/2021
1	Residual Neoplasm 08/2021
1	Neoplasm Metastasis (Metastasis) 08/2021
1	Respiratory Sounds (Crackle) 01/2021
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 11/2020
1	Triple Negative Breast Neoplasms 01/2020
1	Pneumonia (Pneumonitis) 01/2020
1	Familial Primary Pulmonary Hypertension 01/2020
1	Esophageal Squamous Cell Carcinoma 01/2017
1	Takayasu Arteritis (Arteritis, Takayasu's) 09/2016
1	Acute Lung Injury 01/2016
1	Cystic Fibrosis (Mucoviscidosis) 01/2016
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 09/2015
1	Pain (Aches) 08/2015
1	Arteritis 08/2015
1	Hodgkin Disease (Hodgkin's Disease) 05/2015
1	Coronary Artery Disease (Coronary Atherosclerosis) 03/2013

Drug/Important Bio-Agent (IBA)

11	CalciumIBA 01/2022 - 03/2002
8	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 02/2022 - 12/2008
5	Dehydroepiandrosterone (DHEA)IBA 08/2013 - 08/2003
4	Serotonin (5 Hydroxytryptamine)IBA 01/2017 - 06/2004
4	MonocrotalineIBA 01/2017 - 03/2011
3	Adenosine Triphosphate (ATP)IBA 12/2021 - 01/2015
3	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 01/2017 - 03/2006
2	Oxygen (Dioxygen)IBA 01/2020 - 02/2002
2	montelukast (Singulair)FDA Link 01/2018 - 06/2003
2	Vasoconstrictor AgentsIBA 01/2017 - 06/2004
2	A-factor (Streptomyces)IBA 09/2015 - 12/2008
2	Gallopamil (D600)IBA 04/2015 - 06/2011
2	AllergensIBA 03/2015 - 01/2012
2	Glucose (Dextrose)FDA LinkGeneric 01/2015 - 12/2008
2	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2013 - 07/2006
2	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2013 - 07/2006
2	OvalbuminIBA 01/2012 - 07/2003
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 07/2011 - 07/2006
2	Ion Channels (Ion Channel)IBA 04/2008 - 01/2007
2	Propofol (Diprivan)FDA LinkGeneric 03/2006 - 04/2003
2	Etomidate FDA LinkGeneric 03/2006 - 04/2003
1	Interleukin-6 (Interleukin 6)IBA 01/2022
1	Protein Isoforms (Isoforms)IBA 01/2022
1	ChemokinesIBA 01/2022
1	5- (6'- triphenylphosphoniumhexyl)- 5,6- dihydro- 6- phenyl- 3,8- phenanthridinediammineIBA 01/2022
1	LigandsIBA 01/2022
1	rhod-2IBA 01/2022
1	KATP ChannelsIBA 12/2021
1	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 12/2021
1	Fatty Acids (Saturated Fatty Acids)IBA 11/2021
1	naxagolideIBA 11/2020
1	Therapeutic UsesIBA 01/2020
1	Connexin 43 (Connexin43)IBA 01/2020
1	Anti-Asthmatic Agents (Antiasthmatic Drugs)IBA 01/2018
1	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 11/2017
1	RamucirumabIBA 11/2017
1	Contrast MediaIBA 10/2017
1	ErbB Receptors (EGF Receptor)IBA 01/2017
1	Cetuximab (Erbitux)FDA Link 01/2017
1	Chemokine ReceptorsIBA 04/2016
1	plerixafor FDA Link 04/2016
1	TubulinIBA 01/2016
1	ConnexinsIBA 01/2016
1	Actins (F Actin)IBA 01/2016
1	Nerve Growth Factor (NGF)IBA 08/2015
1	Blocking AntibodiesIBA 08/2015
1	CytokinesIBA 08/2015
1	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 04/2015
1	platelet-derived growth factor AIBA 01/2015
1	Bovine Serum AlbuminIBA 01/2015
1	2- (4- cyclopropylphenyl)- N- (1- (5- ((2,2,2- trifluoroethyl)oxo)pyridin- 2- yl)ethyl)acetamideIBA 09/2014
1	T-Type Calcium Channels (T-Type Calcium Channel)IBA 09/2014
1	AntioxidantsIBA 06/2013
1	SteroidsIBA 03/2013

Therapy/Procedure

2	Therapeutics 08/2021 - 01/2017
1	Bronchial Thermoplasty 01/2022
1	Precision Medicine 08/2021
1	Salvage Therapy 05/2015
1	Aftercare (After-Treatment) 04/2015
1	Radiotherapy 11/2014